At least 46 people have been killed after two high-speed trains collided on the railway line connecting Spain’s capital, Madrid, to the southern Andalusia region. The deadly accident prompted the suspension of train services along the busy route as emergency teams responded to the scene.
Rail infrastructure manager Adif and regional civil protection sources confirmed the deaths on Wednesday. Adif announced that traffic on the Madrid-Andalusia high-speed railway had been suspended following what it described as a rear-end collision involving two trains.
The accident involved a Renfe train and an Iryo train, which crashed at approximately 8:54 a.m. local time. A government spokesperson for the Castilla-La Mancha region said two carriages belonging to the Iryo train derailed during the collision. Authorities were still working to establish the full circumstances of the crash and determine the number of injured passengers.
Reports from Spanish news website 20minutos indicated that one of the trains had either stopped or slowed considerably several minutes before the collision because of traffic problems on the railway line. The Renfe train, which was also travelling from Madrid towards Seville, reportedly struck it from behind.

Images broadcast by Castilla-La Mancha Television showed the scale of the destruction, with a derailed train carriage remaining on an elevated section of railway. Twisted metal, broken panels and other wreckage could be seen scattered down the embankment below the tracks.
The collision has also brought renewed attention to railway safety and maintenance in Spain. The latest tragedy comes just nine months after another deadly accident involving high-speed trains operated by the same companies on the same line, which also reportedly claimed 46 lives. That earlier crash occurred near Adamuz in Córdoba province after a train derailed and collided with an oncoming train.
The January accident sparked public debate about investment in railway maintenance and the condition of Spain’s rail infrastructure. El País reported, citing government sources, that investigators were examining whether human error by an Adif employee responding to a fault in the main signalling system could have contributed to the latest crash. However, no official cause had been established.
With train services suspended and investigations underway, authorities face the task of determining exactly what happened before the two trains collided. The latest disaster has left families mourning loved ones and raised fresh questions about the safety of one of Spain’s major high-speed railway routes.